Cáncer » Biomarcadores en Cáncer
Coordinador de Grupo
Rafael Pulido Murillo
Doctor en Biología
Ikerbasque Research Professor
OSI Eskerraldea Enkarterri Cruces
Contacto
(0034) 94 600 6000
Miembros del Grupo
Maider Beitia San Vicente
Goikoane Cancho Galán
Luis Casis Saenz
María del Carmen Etxezarraga Zuluaga
Pedro Francisco García Alonso
Francisco Javier Gil Goikouria
Jon Irazusta Astiazaran
Gorka Larrinaga Enbeitia
Ana Loizaga Iriarte
José Ignacio López Fernández de Villaverde
Sandra Luna Blanco
Alberto Loizate Totorikagüena
Usue Ariz López de Castro
Janire Mingo Gómez de Oteo
Noelia Morales Boiza
Amparo Pérez Fernández
Itxaro Pérez Urzelai
María Begoña Sanz Echevarria
Jon Danel Solano Iturri
Leire Torices Cabarcos
Aitziber Ugalde Olano
Miguel Unda Urzaiz
Líneas de Investigación
Estudio de sistemas peptídicos en cáncer
Fosfatasas y quinasas como biomarcadores y dianas terapéuticas en cáncer
Estudios genotipo-fenotipo de fosfatasas involucradas en cáncer hereditario
Actividades del Grupo
Publicaciones Científicas

He HY, Trpkov K, Martinek P, Isikci OT, Maggi-Galuzzi C, Alaghehbandan R, et al. "High-grade oncocytic renal tumor": morphologic, immunohistochemical, and molecular genetic study of 14 cases. Virchows Arch. 2018; 473(6): 725 - 738. FI: 2,936(Q2). DOI: 10.1007/s00428-018-2456-4.

Mingo J, Rodriguez-Escudero I, Luna S, Fernandez-Acero T, Amo L, Jonasson AR, et al. A pathogenic role for germline PTEN variants which accumulate into the nucleus. Eur. J. Hum. Genet. 2018; 26(8): 1180 - 1187. FI: 3,636(Q2). DOI: 10.1038/s41431-018-0155-x.

Garcia-Gil M, Torres-Unda J, Esain I, Dunabeitia I, Gil SM, Gil J, et al. ANTHROPOMETRIC PARAMETERS, AGE, AND AGILITY AS PERFORMANCE PREDICTORS IN ELITE FEMALE BASKETBALL PLAYERS. J. Strength Cond. Res. 2018; 32(6): 1723 - 1730. FI: 2,325(Q2). DOI: 10.1519/JSC.0000000000002043.

Trpkov K, Athanazio D, Magi-Galluzzi C, Yilmaz H, Clouston D, Agaimy A, et al. Biphasic papillary renal cell carcinoma is a rare morphological variant with frequent multifocality: a study of 28 cases. Histopathology. 2018; 72(5): 777 - 785. FI: 3,267(Q1). DOI: 10.1111/his.13432.

Williamson SR, Rao P, Hes O, Epstein JI, Smith SC, Picken MM, et al. Challenges in Pathologic Staging of Renal Cell Carcinoma A Study of Interobserver Variability Among Urologic Pathologists. Am. J. Surg. Pathol. 2018; 42(9): 1253 - 1261. FI: 5,878(Q1). DOI: 10.1097/PAS.0000000000001087.

Williamson SR, Rao P, Hes O, Epstein J, Picken M, Zhou M, et al. Challenges in Pathologic Staging of Renal Cell Carcinoma: An Interobserver Variability Study of Urologic Pathologists. Mod. Pathol. 2018; 31(2): 399 - 399. MEETING ABSTRACT.

Williamson SR, Rao P, Hes O, Epstein J, Picken M, Zhou M, et al. Challenges in Pathologic Staging of Renal Cell Carcinoma: An Interobserver Variability Study of Urologic Pathologists. Lab. Invest. 2018; 98: 399 - 399. MEETING ABSTRACT.

Turajlic S, Xu H, Litchfield K, Rowan A, Horswell S, Chambers T, et al. Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal. Cell. 2018; 173(3): 595 - 595. FI: 31,398(Q1). DOI: 10.1016/j.cell.2018.03.043.

Aurtenetxe O, Zaldumbide L, Erramuzpe A, Lopez R, Lopez JI, Cortes JM, et al. DUSP5 expression associates with poor prognosis in human neuroblastoma. Exp. Mol. Pathol.. 2018; 105(3): 272 - 278. FI: 2,566(Q2). DOI: 10.1016/j.yexmp.2018.08.008.

Dunabeitia I, Arrieta H, Torres-Unda J, Gil J, Santos-Concejero J, Gil SM, et al. Effects of a capacitive-resistive electric transfer therapy on physiological and biomechanical parameters in recreational runners: A randomized controlled crossover trial. Phys. Ther. Sport. 2018; 32: 227 - 234. FI: 1,919(Q2). DOI: 10.1016/j.ptsp.2018.05.020.

Gianzo M, Urizar-Arenaza I, Munoa-Hoyos I, Larreategui Z, Garrido N, Casis L, et al. Human sperm testicular angiotensin-converting enzyme helps determine human embryo quality. Asian J. Androl.. 2018; 20(5): 498 - 498. FI: 3,259(Q1). DOI: 10.4103/aja.aja_25_18.

Lomana EMF, Munoz AM, Boyano L, Sanz B, Asumendi A, Errarte P, et al. Immunohistochemical expression of Annexin A5 in renal cell carcinomas. Virchows Arch. 2018; 473: 192 - 192. MEETING ABSTRACT.

Erramuzpe A, Cortés JM, López JI. Multisite tumor sampling enhances the detection of intratumor heterogeneity at all different temporal stages of tumor evolution. Virchows Arch. 2018; 472(2): 187 - 194. FI: 2,936(Q2). DOI: 10.1007/s00428-017-2223-y.

Saiz M, Caamano V, Zaldumbide L, Idiondo EFL, Munoz AM, Mosteiro L, et al. Negative Association Between PD1/PD-L1 Inhibitor Expression and ROS1, ALK and EGFR Mutations in Non-Small Cell Lung Cancer. Mod. Pathol.. 2018; 31(2): 749 - 749. MEETING ABSTRACT.

Saiz M, Caamano V, Zaldumbide L, Idiondo EFL, Munoz AM, Mosteiro L, et al. Negative Association Between PD1/PD-L1 Inhibitor Expression and ROS1, ALK and EGFR Mutations in Non-Small Cell Lung Cancer. Lab. Invest. 2018; 98: 749 - 749. MEETING ABSTRACT.

Zaldumbide L, Aurtenetxe O, Erramuzpe A, Saiz M, Lopez-Almaraz R, Caamano V, et al. Neuroblastoma PTPome Analysis Unveils Association of PTPN1 And DUSP5 Expression With Poor Prognosis. Mod. Pathol.. 2018; 31(2): 720 - 720. MEETING ABSTRACT.

Zaldumbide L, Aurtenetxe O, Erramuzpe A, Saiz M, Lopez-Almaraz R, Caamano V, et al. Neuroblastoma PTPome Analysis Unveils Association of PTPN1 And DUSP5 Expression With Poor Prognosis. Lab. Invest. 2018; 98: 720 - 720. MEETING ABSTRACT.

Sanz B, Larrinaga G, Fernandez-Atucha A, Gil J, Fraile-Bermudez AB, Kortajarena M, et al. Obesity parameters, physical activity, and physical fitness are correlated with serum dipeptidyl peptidase IV activity in a healthy population. Heliyon. 2018; 4(5): e00627. FI: (Q). DOI: 10.1016/j.heliyon.2018.e00627.

Solano-Iturri G, García-Jiménez N, Solano-Iturri JD, Blanco-Sampascual S. Olmesartan-associated sprue-like enteropathy: An emerging cause of drug-induced chronic diarrhea. Rev. Gastroenterol. Mex. 2018; 83(1): 71 - 72. FI: (Q). DOI: 10.1016/j.rgmx.2016.06.006.

Beriain ID, Sanz B. Patentability of time-lapse monitoring has nothing to do with human dignity: A response to Alain Pottage. Reprod. Biomed. Online. 2018; 37(4): 390 - 392. FI: 2,967(Q1). DOI: 10.1016/j.rbmo.2018.08.010. EDITORIAL MATERIAL.

Lopez JI, Angulo JC. Pathological Bases and Clinical Impact of Intratumor Heterogeneity in Clear Cell Renal Cell Carcinoma. Curr. Urol. Rep. 2018; 19(1): 3. FI: 1,983(Q3). DOI: 10.1007/s11934-018-0754-7.

Martín-Martín N, Zabala-Letona A, Fernandez-Ruiz S, Arreal L, Camacho L, Castillo-Martin M, et al. PPAR delta Elicits Ligand-Independent Repression of Trefoil Factor Family to Limit Prostate Cancer Growth. Cancer Res. 2018; 78(2): 399 - 409. FI: 9,130(Q1). DOI: 10.1158/0008-5472.CAN-17-0908.

Lomana EMF, Munoz AM, Boyano L, Penas C, Sanz B, de Lezcano ID, et al. Prognostic impact of Pirin expression in clear cell renal cell carcinoma. An immunohistochemical study of 100 cases with long term follow up. Virchows Arch. 2018; 473: 192 - 192. MEETING ABSTRACT.

Munoz AM, Lomana EF, Penas C, Sanz B, Perez I, Asumendi A, et al. Prognostic impact of RKIP expression in clear cell renal cell carcinoma. An immunohistochemical study of 100 cases with long term follow up. Virchows Arch. 2018; 473: 337 - 337. MEETING ABSTRACT.

Hendriks W, Bourgonje A, Leenders W, Pulido R. Proteinaceous Regulators and Inhibitors of Protein Tyrosine Phosphatases. Molecules. 2018; 23(2): 395. FI: 3,098(Q2). DOI: 10.3390/molecules23020395.

Unda-Urzaiz M. Próximos avances en el tratamiento endovesical del tumor vesical no-músculo infiltrante. Arch. Esp. Urol. 2018; 71(4): 328 - 331. FI: 0,465(Q4).

Pulido R. PTEN Inhibition in Human Disease Therapy. Molecules. 2018; 23(2): 285. FI: 3,098(Q2). DOI: 10.3390/molecules23020285. REVIEW.

Unda-Urzaiz M, Sousa-Campo R, Rodríguez-Antolín A, Silva-Marins C, Juárez-Soto A, Miñana-López B, et al. Radium-223 in the therapeutic sequence of metastatic castration-resistant prostate cancer. Actas Urol. Esp. 2018; 42(4): 227 - 237. FI: 1,260(Q4). DOI: 10.1016/j.acuro.2017.05.005. REVIEW.

Unda-Urzaiz M, Alonso-Herreros JM, Fernandez-Gomez JM, Gaspar-Carreño M, Cozar-Olmos JM, Lleti ACC, et al. Review of the evidence on handling drugs and hazardous products in Urology Departments. Consensus document between the Spanish Urological Association and the Spanish Society of Hospital Pharmacy. Actas Urol. Esp. 2018; 42(6): 375 - 380. FI: 1,260(Q4). DOI: 10.1016/j.acuro.2018.03.001. REVIEW.

Li Q, Qiu B, Liang W, Wang J, Hu W, Xu S, et al. Risk Factors of Local Recurrence in EGFR-Mutant Stage III-pN2 Adenocarcinoma After Complete Resection: A Multi-Center Real-World Cohort Study. J. Thorac. Oncol. 2018; 13(10): 617 - 618. FI: 10,336(Q1). DOI: 10.1016/j.jtho.2018.08.949.

Unda-Urzaiz M, Cozar-Olmos JM, Miñana-Lopez B, Camarero-Jimenez J, Brugarolas-Rossello X, Zubiaur-Libano C, et al. Safety and efficacy of various strains of bacille Calmette-Guerin in the treatment of bladder tumours in standard clinical practice. Actas Urol. Esp. 2018; 42(4): 238 - 248. FI: 1,260(Q4). DOI: 10.1016/j.acuro.2017.10.003.

Arenaza IU, Osinalde N, Akimov V, Munoa-Hoyos I, Gianzo M, Ganzabal T, et al. SPANX A/D subfamily plays a key role in nuclear organisation, metabolism and flagellar-motility of human spermatozoa. Hum. Reprod. 2018; 33(1): 58 - 58. MEETING ABSTRACT.

Lopez-Fernandez E, Lopez JI. The Impact of Tumor Eco-Evolution in Renal Cell Carcinoma Sampling. Cancers (Basel). 2018; 10(12): 485. FI: 5,326(Q1). DOI: 10.3390/cancers10120485. REVIEW.

Mingo J, Luna S, Gaafar A, Ruiz R, Carracedo A, Guerra I, et al. The relevance of precision epitope mapping for accurate oncologic diagnostic based on PTEN protein expression in tumours. Virchows Arch. 2018; 473(1): 138 - 138. MEETING ABSTRACT.

Mitchell TJ, Turajlic S, Rowan A, Nicol D, Farmery JHR, O'Brien T, et al. Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal. Cell. 2018; 173(3): 611 - 611. FI: 31,398(Q1). DOI: 10.1016/j.cell.2018.02.020.

Turajlic S, Xu H, Litchfield K, Rowan A, Chambers T, Lopez JI, et al. Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal. Cell. 2018; 173(3): 581 - 581. FI: 31,398(Q1). DOI: 10.1016/j.cell.2018.03.057.

Unda-Urzaiz M, Fernandez-Gomez JM, Cozar-Olmos JM, Juárez A, Palou J, Martínez-Piñeiro L. Update on the role of endovesical chemotherapy in nonmuscle-invasive bladder cancer. Actas Urol. Esp. 2018; 42(2): 73 - 76. FI: 1,260(Q4). DOI: 10.1016/j.acuro.2017.09.006. REVIEW.

Lee JS, Adler L, Karathia H, Carmel N, Rabinovich S, Auslander N, et al. Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures. Cell. 2018; 174(6): 1559 - 1559. FI: 31,398(Q1). DOI: 10.1016/j.cell.2018.07.019.

Baré M, Alcantara MJ, Gil MJ, Collera P, Pont M, Escobar A, et al. Validity of the CR-POSSUM model in surgery for colorectal cancer in Spain (CCR-CARESS study) and comparison with other models to predict operative mortality. BMC Health Serv. Res. 2018; 18(1): 49 - 49. FI: 1,843(Q3). DOI: 10.1186/s12913-018-2839-x.

Alcaraz A, Martínez-Piñeiro L, Rodríguez A, Rubio J, Borque Á, Burgos J, et al. Consenso sobre el manejo del cáncer de próstata resistente a la castración avanzado en España. Arch Esp Urol. 2017;70:777-91. FI:0,323(Q4).

Cortes JM, de Petris G, Lopez JI. Detection of intratumor heterogeneity in modern pathology: a multisite tumor sampling perspective. Front Med. 2017;4:25. DOI:10.3389/fmed.2017.00025.

De Petris G, De Marco L, Lopez JI. Drug-induced gastrointestinal injury (DIGI). Updates, reflections and key points. Pathologica. 2017;109:97-109.

Errarte P, Beitia M, Perez I, Manterola L, Lawrie CH, Solano-Iturri JD, et al. Expression and activity of angiotensin-regulating enzymes is associated with prognostic outcome in clear cell renal cell carcinoma patients. PLoS One. 2017;12:e0181711. FI:2,806(Q1). DOI:10.1371/journal.pone.0181711.

Fraile-Bermúdez AB, Kortajarena M, Zarrazquin I, Irazusta A, Fernandez-Atutxa A, Ruiz-Litago F, et al. Physical activity and dietary habits related to cardiovascular risk in independent community-living older women. Exp Gerontol. 2017;92:46-51. FI:3,340(Q1). DOI: 10.1016/j.exger.2017.03.012.

Garcia-Ariza M, Echebarria Barona A, Lopez-Almaraz R, Adan Pedroso R, Bilbao Salcines N, Ricondo De Diego A, et al. Tumors of the central nervous system in the first year of life. One single institution experience. Pediatr Blood Cancer. 2017;64:462. FI:2,513(Q1). ABSTRACT

Garcia-Ariza M, Lopez-Almaraz R, Echebarria Barona A, Adan Pedroso R, Ojinaga Nino I, Ricondo De Diego A, et al. Experience of the management of central nervous system tumors in;children younger than 5 years-old in the last 15 years. Pediatr Blood Cancer. 2017;64:304. FI:2,513(Q1). ABSTRACT

Gianzo M, Larreategui Z, Munoa-Hoyos I, Urizar-Arenaza I, Irazusta J, Subiran N. The (Pro)renin receptor is expressed in human sperm cells and is related to sperm quality and embryo development. Hum Reprod. 2017;32:154-5. FI:5,020(Q1). ABSTRACT

Gomez-Iturriaga A, Casquero F, Lopez JI, Urresola A, Ezquerro A, Buscher D, et al. Transperineal biopsies of MRI-detected aggressive index lesions in low-and intermediate-risk prostate cancer patients Implications for treatment decision. Brachytherapy. 2017;16:201-6. FI:2,082(Q2). DOI:10.1016/j.brachy.2016.11.004.

Gómez-Veiga F, Rodríguez-Antolín A, Miñana B, Hernández C, Suárez JF, Fernández-Gómez JM, et al. Diagnosis and treatment for clinically localized prostate cancer. Adherence to the European Association of Urology clinical guidelines in a nationwide population-based study - GESCAP group. Actas Urol Esp. 2017;41:359-67. FI:1,181(Q4). DOI: 10.1016/j.acuro.2016.10.009.

Loizaga-Iriarte A, Rodriguez-Antolin A, Miñana B, Lacasa-Viscasillas I, Senarriaga-Ruiz de la Illa, N, Cozar-Olmo JM, et al. Castrate resistant prostate cancer. Consensus recommendations of the Spanish Association of Urology. Actas Urol Esp. 2017;41:141-5. FI:1,181(Q4). DOI:10.1016/j.acuro.2016.09.001. EDITORIAL MATERIAL

López JI, Angulo JC, Martin A, Sanchez-Chapado M, Gonzalez-Corpas A, Colas B, et al. A DNA hypermethylation profile reveals new potential biomarkers for the evaluation of prognosis in urothelial bladder cancer. APMIS. 2017;125:787-96. FI:1,795(Q3). DOI:10.1111/apm.12719.

López JI, Cortés JM. Multisite tumor sampling: a new tumor selection method to enhance intratumor heterogeneity detection. Hum Pathol. 2017;64:1-6. FI:3,014(Q1). DOI:10.1016/j.humpath.2017.02.010.

López JI, De Petris G. Discovering intratumor heterogeneity:the next frontier for pathologists. Pathologica. 2017;109:110-3.

López JI, Erramuzpe A, Guarch R, Cortés JM, Pulido R, Llarena R, et al. CD34 immunostaining enhances a distinct pattern of intratumor angiogenesis with prognostic implications in clear cell renal cell carcinoma. APMIS. 2017;125:128-33. FI:1,795(Q3). DOI:10.1111/apm.12649.

Luna S, Mingo J, Amo L, Rodriguez-Escudero I, Erramuzpe A, Molina M, et al. Readthrough response of pathogenic premature termination codons at PTEN;gene:implications in precision therapy for PHTS patients. Ann Oncol. 2017;28:18. FI:11,855(Q1). ABSTRACT

Miles J, Applebee CJ, Leboucher P, Lopez-Fernandez S, Lee DJ, Guarch R, et al. Time resolved amplified FRET identifies protein kinase B activation; state as a marker for poor prognosis in clear cell renal cell carcinoma. BBA Clin. 2017;8:97-102. DOI:10.1016/j.bbacli.2017.10.002.

Mingo J, Luna S, Gaafar A, Ruiz R, Carracedo A, Guerra I, et al. The relevance of precision epitope mapping for accurate oncologic; diagnostic based on PTEN protein expression in tumours. Ann Oncol. 2017;28:21. FI:11,855(Q1). ABSTRACT

Oliver MD, Fernández-Acero T, Luna S, Rodríguez-Escudero I, Molina M, Pulido R, et al. Insights into the pathological mechanisms of p85a mutations using a yeast-based phosphatidylinositol 3-kinase model. Biosci Rep. 2017;37:2. FI:2,906(Q2). DOI:10.1042/BSR20160258.

Panfoli I, Ponassi M, Ravera S, Calzia D, Beitia M, Morelli A, et al. Tracking protons from respiratory chain complexes to ATP synthase c-subunit: The critical role of serine and threonine residues. Biochem Biophys Res Commun. 2017;482:922-7. FI:2,466(Q3). DOI:10.1016/j.bbrc.2016.11.134.

Pulido R, Nunes-Xavier C, Aurtenetxe O, Zaldumbide L, Erramuzpe A, Lopez R, et al. Neuroblastoma PTPome analysis unveils association of DUSP5 and PTPN1 expression with poor prognosis. Ann Oncol. 2017;28:57. FI:11,855(Q1). ABSTRACT

Solano-Iturri G, García-Jiménez N, Solano-Iturri JD, Blanco-Sampascual S. Olmesartan-associated sprue-like enteropathy: An emerging cause of drug-induced chronic diarrhea. Revista de Gastroenterologia de Mexico. 2017;83:71-2. DOI:10.1016/j.rgmx.2016.06.006.

Tamayo-Orbegozo E, Amo L, Riñón M, Nieto N, Amutio E, Maruri N, et al. Podocalyxin promotes proliferation and survival in mature B-cell; non-Hodgkin lymphoma cells. Oncotarget. 2017;8:99722-39. FI:5,168(Q1). DOI:10.18632/oncotarget.21283.

Torres-Unda J, Polo V, Dunabeitia I, Bidaurrazaga-Letona I, Garcia-Gil M, Rodriguez-Larrad A, et al. The Feldenkrais Method improves functioning and body balance in people; with intellectual disability in supported employment: A randomized; clinical trial. Res Dev Disabil. 2017;70:104-12. FI:1,630(Q1). DOI:10.1016/j.ridd.2017.08.012.

Trpkov K, Abou-Ouf H, Hes O, Lopez JI, Nesi G, Comperat E, et al. Eosinophilic Solid and Cystic Renal Cell Carcinoma (ESC RCC) Further Morphologic and Molecular Characterization of ESC RCC as a Distinct Entity. Am J Surg Pathol. 2017;41:1299-308. FI:5,363(Q1).

Trpkov K, Athanazio D, Magi-Galluzzi C, Yilmaz H, Clouston D, Agaimy A, et al. Biphasic Papillary Renal Cell Carcinoma Is a Rare and Distinct Morphologic Variant Clinicopathologic Study of 24 Novel Cases. Lab Invest. 2017;97:266. FI:4,857(Q1). ABSTRACT

Trpkov K, Athanazio D, Magi-Galluzzi C, Yilmaz H, Clouston D, Agaimy A, et al. Biphasic Papillary Renal Cell Carcinoma Is a Rare and Distinct; Morphologic Variant Clinicopathologic Study of 24 Novel Cases. Mod Pathol. 2017;30:2640. FI:5,728(Q1). ABSTRACT

Urizar-Arenaza I, Osinalde N, Gianzo M, Matorras R, Exposito A, Irazusta J, et al. Label-free phosphoproteomics reveals a novel calcium signaling pathway; activated via kappa-opioid receptor in human spermatozoa. Hum Reprod. 2017;32:58-9. FI:5,020(Q1). ABSTRACT

Wong KK, Hussain FA, Loo SK and Lopez JI. Cancer/testis antigen SPATA19 is frequently expressed in benign prostatic hyperplasia and prostate cancer. APMIS. 2017;125:1092-101. FI:1,795(Q3). DOI:10.1111/apm.12775.

Zabala-Letona A, Arruabarrena-Aristorena A, Martín-Martín N, Fernandez-Ruiz S, Sutherland JD, Clasquin M, et al. MTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer. Nature. 2017;547:109-13. FI:40,137(Q1). DOI:10.1038/nature22964.

Alcaraz A, Carballido-Rodriguez J, Unda-Urzaiz M, Medina-Lopez R, Ruiz-Cerda JL, Rodriguez-Rubio F, et al. Quality of life in patients with lower urinary tract symptoms associated with BPH: change over time in real-life practice according to treatment-the QUALIPROST study. Int Urol Nephrol. 2016;48:645-56. FI:1,564(Q3). DOI:10.1007/s11255-015-1206-7.

Alonso A, Nunes-Xavier CE, Bayón Y, Pulido R. The Extended Family of Protein Tyrosine Phosphatases. Methods Mol Biol. 2016;1447:1-23. DOI:10.1007/978-1-4939-3746-2_1.

Alonso, Andres, Pulido, Rafael. The extended human PTPome: a growing tyrosine phosphatase family. FEBS J. 2016;283:1404-29. FI:3,902(Q2). DOI:10.1111/febs.13600.

Angulo JC, López JI, Fernández-Arias M. Revealing the production process of Joaquín Albarrán's Les Tumeurs de la Vessie 125 years after its writing. Actas Urol Esp. 2016;40:463-9. FI:1,181(Q4). DOI:10.1016/j.acuro.2016.01.008.

Angulo JC, Andrés G, Ashour N, Sánchez-Chapado M, López JI, Ropero S. Development of Castration Resistant Prostate Cancer can be Predicted by a DNA Hypermethylation Profile. J Urol. 2016;195:619-26. FI:5,157(Q1). DOI:10.1016/j.juro.2015.10.172.

Angulo JC, Lopez JI, Dorado JF, Sanchez-Chapado M, Colas B, Ropero S. A DNA Hypermethylation Profile Independently Predicts Biochemical Recurrence Following Radical Prostatectomy. Urol Int. 2016; 97:16-25. FI:1,611(Q3). DOI:10.1159/000446446.

Angulo JC, López JI, Ropero S. DNA Methylation and Urological Cancer, a Step Towards Personalized Medicine: Current and Future Prospects. Mol Diagn Ther. 2016;20:531-49. FI:1,909(Q3). DOI:10.1007/s40291-016-0231-2.

Angulo JC, Redondo C, Sánchez-Chapado M, Colás B, Ropero S, López JI. Survival predictors in patients with prostate adenocarcinoma with hormonal blockade. Pathol Res Pract. 2016;212:899-903. FI:1,543(Q3). DOI:10.1016/j.prp.2016.07.012.

Arrieta H, Torres-Unda J, Gil SM, Irazusta J. Relative age effect and performance in the U16, U18 and U20 European Basketball Championships. J Sports Sci. 2016;34:1530-4. FI:2,539(Q1). DOI:10.1080/02640414.2015.1122204.

Errarte P, Guarch R, Pulido R, Blanco L, Nunes-Xavier CE, Beitia M, et al. The Expression of Fibroblast Activation Protein in Clear Cell Renal Cell Carcinomas Is Associated with Synchronous Lymph Node Metastases. PLoS One. 2016;11:e0169105. FI:2,806(Q1). DOI:10.1371/journal.pone.0169105.

Foix MP, Dunatov A, Martinek P, Mundó EC, Suster S, Sperga M, et al. Morphological, immunohistochemical, and chromosomal analysis of multicystic chromophobe renal cell carcinoma, an architecturally unusual challenging variant. Virchows Arch. 2016;469:669-78. FI:2,848(Q2). DOI:10.1007/s00428-016-2022-x.

Foix MP, Dunatov A, Martinek, P, Condom-Mundo E, Suster S, Sperga M, et al. Multicystic Chromophobe Renal Cell Carcinoma: A Challenging Unusual Architectural Variant. Morphological, Immunohistochemical and arrayCGH Analysis of 11 Cases. Mod Pathol. 2016; 29:253-4. FI:5,728(Q1).

Foix MP, Dunatov A, Martinek P, Condom-Mundo E, Suster S, Sperga M, et al. Multicystic Chromophobe Renal Cell Carcinoma: A Challenging Unusual Architectural Variant. Morphological, Immunohistochemical and arrayCGH Analysis of 11 Cases. Lab Invest. 2016; 96:253-4. FI:4,857(Q1). ABSTRACT

Gianzo M, Munoa-Hoyos I, Urizar-Arenaza I, Larreategui Z, Quintana F, Garrido N, et al. Angiotensin II type 2 receptor is expressed in human sperm cells and is involved in sperm motility. Fertil Steril. 2016;105:608-16. FI:4,373(Q1). DOI:10.1016/j.fertnstert.2015.11.004.

Gil A, López JI, Pulido R. Assessing PTEN Subcellular Localization. Methods Mol Biol. 2016;1388:169-86. DOI:10.1007/978-1-4939-3299-3_12.

Gomez-Iturriaga A, Casquero F, Urresola A, Ezquerro A, Lopez JI, Espinosa JM, et al. Dose escalation to dominant intraprostatic lesions with MRI-transrectal ultrasound fusion High-Dose-Rate prostate brachytherapy. Prospective phase II trial. Radiother Oncol. 2016;119:91-6. FI:4,328(Q1). DOI:10.1016/j.radonc.2016.02.004.

Hes O, Mundo EC, Peckova K, Lopez JI, Martinek P, Vanecek T, et al. Biphasic Squamoid Alveolar Renal Cell Carcinoma: A Distinctive Subtype of Papillary Renal Cell Carcinoma?. Am J Surg Pathol. 2016;40:664-75. FI:5,363(Q1). DOI:10.1097/PAS.0000000000000639.

Knafo S, Sanchez-Puelles C, Palomer E, Delgado I, Draffin JE, Mingo J, et al. PTEN recruitment controls synaptic and cognitive function in Alzheimer's models. Nat Neurosci. 2016; 19:443. FI:17,839(Q1). DOI:10.1038/nn.4225.

Lopez JI, Cortes JM. A divide-and-conquer strategy in tumor sampling enhances detection of intratumor heterogeneity in routine pathology: A modeling approach in clear cell renal cell carcinoma. F1000Res. 2016;5:385. DOI:10.12688/f1000research.8196.2. SIN FI

Lopez JI, Cortes JM. A multi-site cutting device implements efficiently the divide-and-conquer strategy in tumor sampling.Version 2. F1000Res. 2016;5:1587. DOI:10.12688/f1000research.9091.2.

Lopez JI. Case Report: Multifocal biphasic squamoid alveolar renal cell carcinoma. F1000Res. 2016;5:607. DOI:10.12688/f1000research.8451.2.

López JI, Errarte P, Erramuzpe A, Guarch R, Cortés JM, Angulo JC, et al. Fibroblast activation protein predicts prognosis in clear cell renal cell carcinoma. Hum Pathol. 2016;54:100-5. FI:3,014(Q1). DOI:10.1016/j.humpath.2016.03.009.

López JI, Mosteiro L, Guarch R, Larrinaga G, Pulido R, Angulo JC. Low-grade metastases in high-grade clear cell renal cell carcinomas: A clinicopathologic study of 4 cases with an insight into the role of mesenchymal-toepithelial transition process. Ann Diagn Pathol. 2016;20:13-8. FI:1,734(Q3). DOI:10.1016/j.anndiagpath.2015.10.011.

López JI. Gleason and Fuhrman no longer make the grade. Histopathology. 2016;69:340-1. FI:3,523(Q1). DOI:10.1111/his.12946.

López JI. Intratumor heterogeneity in clear cell renal cell carcinoma: a review for the practicing pathologist. APMIS. 2016;124:153-9. FI:1,795(Q3). DOI:10.1111/apm.12500.

Luna S, Mingo J, Aurtenetxe O, Blanco L, Amo L, Schepens J, et al. Tailor-Made Protein Tyrosine Phosphatases: In Vitro Site-Directed Mutagenesis of PTEN and PTPRZ-B. Methods Mol Biol. 2016;1447:79-93. DOI:10.1007/978-1-4939-3746-2_5.

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Palou-Redorta J, Solsona E, Angulo J, Fernández JM, Madero R, Unda M, et al. Retrospective study of various conservative treatment options with bacille Calmette-Guérin in bladder urothelial carcinoma T1G3: Maintenance therapy. Actas Urol Esp. 2016;40: 370-7. FI:1,181(Q4). DOI:10.1016/j.acuro.2015.12.009.

Planelles M, Macías L, Peiró G, Bulimbasic S, Hes O, Robles A, et al. Rheb/mTOR/p70s6k Cascade and TFE3 Expression in Conventional and Sclerosing PEComas of the Urinary Tract. Appl Immunohistochem. 2016;24:514-20. FI:1,634(Q2). DOI:10.1097/PAI.0000000000000209.

Royo F, Zuñiga-Garcia P, Torrano V, Loizaga A, Sanchez-Mosquera P, Ugalde-Olano A, et al. Transcriptomic profiling of urine extracellular vesicles reveals alterations of CDH3 in prostate cancer. Oncotarget. 2016;7:6835-46. FI:5,168(Q1). DOI:10.18632/oncotarget.6899.

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Torrano V, Royo F, Peinado H, Loizaga-Iriarte, Unda M, Falcon-Perez JM, et al. Vesicle-MaNiA: Extracellular vesicles in liquid biopsy and cancer. Curr Opin Pharmacol. 2016;29:47-53. FI:5,363(Q1). DOI:10.1016/j.coph.2016.06.003.

Trpkov K, Hes O, Bonert M, Lopez JI, Bonsib SM, Nesi G, et al. Eosinophilic, Solid, and Cystic Renal Cell Carcinoma: Clinicopathologic Study of 16 Unique, Sporadic Neoplasms Occurring in Women. Am J Surg Pathol. 2016;40:60-71. FI:5,363(Q1). DOI:10.1097/PAS.0000000000000508.

Trpkov K, Abou-Ouf H, Hes O, Lopez JI, Nesi G, Comperat E, et al. Eosinophilic Solid and Cystic Renal Cell Carcinoma (ESC RCC): A Novel Entity with Distinct Molecular Karyotype. Lab Invest. 2016;96:267. FI:4,857(Q1). ABSTRACT

Trpkov K, Abou-Ouf H, Hes O, Lopez JI, Nesi G, Comperat E, et al. Eosinophilic Solid and Cystic Renal Cell Carcinoma (ESC RCC): A Novel Entity with Distinct Molecular Karyotype. Mod Pathol. 2016;29:267. FI:5,728(Q1). ABSTRACT

Urizar-Arenaza I, Estomba H, Muñoa-Hoyos I, Matorras R, Esposito A, Candenas L, et al. The opioid peptide beta-endorphin stimulates acrosome reaction in human spermatozoa.Andrology. 2016;4:143-51. FI:2,427(Q2). DOI:10.1111/andr.12133.

Caamaño Villaverde V, Mosteiro L, Guarch R, Pulido R, López JI. Low-grade metastases from Clear Cell Renal Cell Carcinomas (CCRCC): A study of E- and N- Cadherin expression in 19 cases. Virchows Arch. 2016;469:336. FI:2,848(Q2). ABSTRACT

Zaldumbide L, Erramuzpe A, Guarch R, Pulido R, Cortés JM, López JI. Snail heterogeneity in clear cell renal cell carcinoma. BMC Cancer. 2016;16:194. FI:3,288(Q2). DOI:10.1186/s12885-016-2237-x.

Amo L, Tamayo-Orbegozo E, Maruri N, Buque A, Solaun M, Rinon M, et al. Podocalyxin-like protein 1 functions as an immunomodulatory molecule in breast cancer cells. Cancer Lett. 2015;368:26-35. FI:5,992(Q1). DOI:10.1016/j.canlet.2015.06.029.

Fernandez-Atucha A, Echevarria E, Larrinaga G, Gil J, Martinez-Cengotitabengoa M, Gonzalez-Pinto AM, et al. Plasma peptidases as prognostic biomarkers in patients with first-episode psychosis. Psychiat Res. 2015;228:197-202. FI:2,466(Q2). DOI:10.1016/j.psychres.2015.04.027.

Gil A, Rodriguez-Escudero I, Stumpf M, Molina M, Cid VJ, Pulido R. A functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activity. PLoS One. 2015;10. FI:3,057(Q1). DOI:10.1371/journal.pone.0119287.

Hen O, Condom-Mundo E, Lopez J, Peckova K, Martinek P, Rotterova P, et al. Biphasic squamoid alveolar renal cell carcinoma is probably part of the spectrum of papillary renal cell carcinoma: Clinicopathologic, immunohistochemical and molecular genetic analysis of 22 cases. Lab Invest. 2015;95:228-0. FI:4,202(Q1). ABSTRACT

Kuroda N, Karashima T, Inoue K, Kasajima A, Ohe C, Kawakami F, et al. Review of renal cell carcinoma with rhabdoid features with focus on clinical and pathobiological aspects. Pol J Pathol. 2015;66:3-8. FI:1,240(Q3). DOI:10.5114/PJP.2015.51147.

Larrinaga G, Perez I, Sanz B, Beitia M, Errarte P, Fernandez A, et al. Dipeptidyl-peptidase IV activity is correlated with colorectal cancer prognosis. PLoS One. 2015;10. FI:3,057(Q1). DOI:10.1371/journal.pone.0119436.

Lopez JI, Larrinaga G, Kuroda N, Angulo JC. The normal and pathologic renal medulla: A comprehensive overview. Pathol Res Pract. 2015;211:271-280. FI:1,388(Q3). DOI:10.1016/j.prp.2014.12.009.

Munoa I, Urizar I, Casis L, Irazusta J, Subiran N. The Epigenetic Regulation of the Opioid System: New individualized prompt prevention and treatment strategies. J Cell Biochem. 2015;116:2419-2426. FI:3,446(Q2). DOI:10.1002/jcb.25222.

Peckova K, Martinek P, Ohe C, Kuroda N, Bulimbasic S, Condom-Mundo E, et al. Chromophobe renal cell carcinoma with neuroendocrine and neuroendocrine-like features. Morphologic, immunohistochemical, ultrastructural, and array comparative genomic hybridization analysis of 18 cases and review of the literature. Ann Diagn Pathol. 2015;19:261-268. FI:1,022(Q4). DOI:10.1016/j.anndiagpath.2015.05.001.

Peckova K, Ohe C, Kuroda N, Martinek P, Bulimbasic S, Montiel DP, et al. Chromophobe renal cell carcinoma with neuroendocrine differentiation and neuroendocrine-like features. Morphologic, immunohistochemical, ultrastructural, and arrayCGH analysis of 18 cases. Lab Invest. 2015;95:250. FI:4,202(Q1). ABSTRACT

Peckova K, Ohe C, Kuroda N, Martinek P, Bulimbasic S, Montiel DP, et al. Chromophobe renal cell carcinoma with neuroendocrine differentiation and neuroendocrine-like features. Morphologic, immunohistochemical, ultrastructural, and arrayCGH analysis of 18 cases. Modern Pathol. 2015;28:250-0. FI:5,485(Q1). ABSTRACT

Perez I, Blanco L, Sanz B, Errarte P, Ariz U, Beitia M, et al. Altered activity and expression of cytosolic peptidases in colorectal cancer. Int J Med Sci. 2015;12:458-467. FI:2,232(Q1). DOI:10.7150/ijms.11808.

Pulido R. A rapid guide to PTEN function. Methods. 2015;77-78:1-2. FI:3,503(Q1). DOI:10.1016/j.ymeth.2015.02.006. EDITORIAL MATERIAL

Pulido R. PTEN: A yin-yang master regulator protein in health and disease. Methods. 2015;77-78:3-10. FI:3,503(Q1). DOI:10.1016/j.ymeth.2015.02.009.

Rodriguez-Escudero I, Fernandez-Acero T, Bravo I, Leslie NR, Pulido R, Molina M, et al. Yeast-based methods to assess PTEN phosphoinositide phosphatase activity in vivo. Methods. 2015;77-78:172-179. FI:3,503(Q1). DOI:10.1016/j.ymeth.2014.10.020.

Ruiz de Garibay G, Herranz C, Llorente A, Boni J, Serra-Musach J, Mateo F, el al. Lymphangioleiomyomatosis biomarkers linked to lung metastatic potential and cell stemness. PLoS One. 2015;. FI:3,057(Q1). DOI:10.1371/journal.pone.0132546.

Sanz B, Perez I, Beitia M, Errarte P, Fernandez A, Blanco L, et al. Aminopeptidase N activity predicts 5-year survival in colorectal cancer patients. J. Invest. Med. 2015;63:740-746. FI:1,688(Q2). DOI:10.1097/JIM.0000000000000199.

Solsona E, Madero R, Chantada V, Fernandez JM, Zabala JA, Portillo JA, et al. Sequential combination of mitomycin C plus Bacillus Calmette-Guerin (BCG) is more effective but more toxic than bcg alone in patients with non-muscle-invasive bladder cancer in intermediate-and high-risk patients: Final outcome of CUETO 93009, a Randomized Prospective Trial. Eur Urol. 2015;67:508-516. FI:14,976(Q1). DOI:10.1016/j.eururo.2014.09.026.

Sotelo NS, Schepens JTG, Valiente M, Hendriks WJAJ, Pulido R. PTEN-PDZ domain interactions: Binding of PTEN to PDZ domains of PTPN13. Methods. 2015;77-78:147-156. FI:3,503(Q1). DOI:10.1016/j.ymeth.2014.10.017.

Ugalde-Olano A, Egia A, Fernandez-Ruiz S, Loizaga-Iriarte A, Zuniga-Garcia P, Garcia S, et al. Methodological aspects of the molecular and histological study of prostate cancer: Focus on PTEN. Methods. 2015;77:25-30. FI:3,503(Q1). DOI:10.1016/j.ymeth.2015.02.005.

Urizar I, Munoa I, Gianzo M, Estomba H, Matorras R, Exposito A, et al. The Kappa-opioid receptor modulates the human sperm capacitation and acrosome reaction. Hum Reprod. 2015;30:174-175. FI:4,621(Q1). ABSTRACT

Zaldumbide L, Erramuzpe A, Guarch R, Cortés JM, López JI. Large (> 3.8 cm) clear cell renal cell carcinomas are morphologically and immunohistochemically heterogeneous. Virchows Arch. 2015;466:61-66. FI:2,613(Q2). DOI:10.1007/s00428-014-1673-8.

Santos-Concejero J, Tam N, Granados C, Irazusta J, Bidaurrazaga-Letona I, Zabala-Lili J, et al. Interaction Effects of Stride Angle and Strike Pattern on Running Economy. Int J Sports Med. 2014;35:1118-23. FI: 2,065(Q2)

López JI, Cáceres F, Pérez A, Caamaño V, Larrinaga G, Lecumberri D, et al. Diagnostic Usefulness of the Cytological Study of the Transport Buffer in Transrectal Prostate Core Biopsies. Actas Urol Esp. 2014;38:566-70. FI: 1,022(Q4)

García-Tello A, Ramón de Fata F, Andrés G, Ropero S, López JI, Angulo JC. DNA repair genes and prognosis in sporadic forms of urotheliat carcinoma of the upper urinary tract. Actas Urol Esp. 2014;38:600-7. FI: 1,022(Q4)

Zarrazquin I, Torres-Unda J, Ruiz F, Irazusta J, Kortajarena M, Hoyos Cillero I, et al. Longitudinal study: lifestyle and cardiovascular health in health science students. Nutr Hosp. 2014;30:1144-51. FI: 1,040(Q4)

García-Tello A, Angulo JC, Andrés G, Ramón de Fata F, Sánchez-Chapado M, López JI. Impact of p53, MIB-1 and PECAM-1 expression on the prognosis of urothelial carcinoma of the renal pelvis. Actas Urol Esp. 2014;38:506-14. FI: 1,022(Q4)

Santos-Concejero J, Granados C, Irazusta J, Bidaurrazaga-Letona I, Zabala-Lili J, Tam N, et al. OBLA is a better predictor of performance than Dmax in long and middle-distance well-trained runners. J Sports Med Phys Fit. 2014;54:553-8. FI: 0,972(Q3)

Ashour N, Angulo JC, Andrés G, Alelú R, González-Corpas A, Toledo MV, et al. A DNA Hypermethylation Profile Reveals New Potential Biomarkers for Prostate Cancer Diagnosis and Prognosis. Prostate. 2014;74:1171-82. FI: 3,565(Q1)

García-Tello A, Angulo JC, Rodriguez-Ubreva J, Andrés G, López JI, Sánchez-Chapado M, et al. Prostate anatomy in motheaten viable (me(v)) mice with mutations in the protein tyrosine phosphatase SHP-1. Actas Urol Esp. 2014;38:438-44. FI: 1,022(Q4)

Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin-Sang ID, et al. A Unified Nomenclature and Amino Acid Numbering for Human PTEN. Sci Signal. 2014;7:pe15 .FI: 6,279(Q1)

Santos-Concejero J, Tam N, Granados C, Irazusta J, Bidaurrazaga-Letona I, Zabala-Lili J, et al. Stride angle as a novel indicator of running economy in well-trained runners. J Strength Cond Res. 2014;28:1889-95. FI: 2,075(Q2)

Blanco L, Sanz B, Perez I, Sánchez CE, Cándenas ML, Pinto FM, et al. Altered glutamyl-aminopeptidase activity and expression in renal neoplasms. BMC Cancer. 2014; 14:386. FI: 3,362(Q2)

Santos-Concejero J, Tucker R, Granados C, Irazusta J, Bidaurrazaga-Letona I, Zabala-Lili J, et al. Influence of regression model and initial intensity of an incremental test on the relationship between the lactate threshold estimated by the maximal-deviation method and running performance. J Sports Sci. 2014;32:853-9. FI: 2,246(Q1)

Lawrie CH, Larrea E, Larrinaga G, Goicoechea I, Arestin M, Fernandez-Mercado M, et al. Targeted next-generation sequencing and non-coding RNA expression analysis of clear cell papillary renal cell carcinoma suggests distinct pathological mechanisms from other renal tumour subtypes. J Pathol. 2014;232:32-42. FI: 7,429(Q1)

Larrinaga G, Perez I, Blanco L, Sanz B, Errarte P, Beitia M, et al. Prolyl Endopeptidase Activity Is Correlated with Colorectal Cancer Prognosis. Int J Med Sci. 2014;11:199-208. FI: 2,003(Q2)

Corominas Cishek A, Gonzalez M, Caamano V, Andueza E, Cerda N, Lopez JI. Biphasic alveolo-squamoid renal carcinoma (BASRC): Light and immunohistochemical study of 3 cases. Virchows Arch. 2014; 465:157. FI: 2,651(Q2)

Cerda N, Planelles M, Macias L, Bulimbasic S, Peiro G, Robles A, et al. Urinary tract Perivascular Epithelioid Cell tumour (PEComa): Clinical, histological, and immunohistochemical study of Rheb/mTOR/p70s6k cascade in 9 cases. Virchows Arch. 2014;465:161. FI: 2,651(Q2)

Caamano Villaverde V, Lopez JI, Andueza E, Gonzalez M, Cerda N, Corominas A, et al. Tubular renal cell carcinoma with prominent cytoplasmic vacuolization: Report of two cases of a previously non described phenotype. Virchows Arch. 2014;465:263-4. FI: 2,651(Q2)

Corominas Cishek A, Guarch R, Erramuzpe A, Zaldumbide L, Cerda N, Andueza E, et al. Parameters predicting intratumor heterogeneity in clear cell renal cell carcinoma. Virchows Arch. 2014;465:158. FI: 2,651(Q2)

Aurtenetxe O, Gaffar A, Gros L, Cruz O, Calvo C, Navajas A. Follow up of spanish childhood medulloblastoma. Neuro-Oncology. 2014;16:93. FI: 5,562(Q1)

Castillejo A, Sanchez-Heras AB, Egoavil C, Esquembre C, Castillejo M, Martinez-Canto A, et al. Colorectal Cancer in Hereditary Leiomyomatosis and Renal Cell Carcionoma Syndrome (HLRCC). Lab Invest. 2014;94:470. FI: 3,676(Q1)

Castillejo A, Sanchez-Heras AB, Egoavil C, Esquembre C, Castillejo M, Martinez-Canto A, et al. Colorectal Cancer in Hereditary Leiomyomatosis and Renal Cell Carcionoma Syndrome (HLRCC). Mod Pathol. 2014;27:4700. FI: 6,187(Q1)

Ríos P, Nunes-Xavier CE, Tabernero L, Köhn M, Pulido R. Dual-Specificity Phosphatases as Molecular Targets for Inhibition in Human Disease. Antioxid Redox Signal. 2014;20:2251-73. FI: 7,407(Q1)

Kuroda N, Ohe C, Kawakami F, Mikami S, Furuya M, Matsuura K, et al. . Clear cell papillary renal cell carcinoma: a review. Int J Clin Exp Pathol. 2014;7:7312-8. FI: 1,891(Q3)

Lopez JI, Guarch R, Larrinaga G, Corominas-Cishek A, Orozco R. Cell heterogeneity in clear cell renal cell carcinoma. APMIS. 2013;121:1187-91. FI: 2,068(Q2)

López JI, Schiavo-Lena M, Corominas-Cishek A, Yagüe A, Bauleth K, Guarch R, et al. Nephrogenic adenoma of the urinary tract: clinical, histological, and immunohistochemical characteristics. Virchows Arch. 2013;463:819-25. FI: 2,676(Q2)

Larrinaga G, Perez I, Ariz U, Sanz B, Beitia M, Errarte P, et al. Clinical impact of aspartylaminopeptidase expression and activity in colorectal cancer. Transl Res. 2013;162:297-308. FI: 3,490(Q1)

Cejudo-Roman A, Pinto FM, Subiran N, Ravina CG, Fernandez-Sanchez M, Perez-Hernandez N,  et al. The Voltage-Gated Sodium Channel Na(v)1.8 Is Expressed in Human Sperm. PLoS One. 2013;8:e76084  FI: 3,730(Q1)

Corominas-Cishek A, Schiavo-Lena M, Macias L, Yaguee A, Guarch R, Tardanico R, et al. Nephrogenic adenoma/metaplasia: A multicenter clinicopathological study of 106 cases. Virchows Arch. 2013;463:123. FI: 2,676(Q2). ( Meeting Abstract).

Corominas-Cishek A, Gonzalez M, Perez A, Caamano V, Muniz G, Cerda N, et al. BRAF V600E mutation is associated with aggressive behaviour in the papillary variant of papillary thyroid carcinoma. Virchows Arch. 2013;463:152. FI: 2,676(Q2). ( Meeting Abstract).

Caamano Villaverde V, Schiavo-Lena M, Yaguee A, Zaldumbide L, Guarch R, Tardanico R, et al Metastases into renal cell carcinomas.Virchows Arch. 2013;463:331-2. FI: 2,676(Q2). ( Meeting Abstract)

Caamano Villaverde V, Muniz G, Corominas-Cishek A, Cerda N, Perez A, Gonzalez M, et al. Nodular adenocarcinoma of the prostate with leiomyomatousstroma: Report of 3 cases of an underecognized histological phenotype. Virchows Arch. 2013;463:331.  FI: 2,676(Q2). ( Meeting Abstract)

Cerda N, Corominas-Cishek  A, Muniz G, Caamano V, Perez A, Gonzalez M, et al. Nested variant of urothelial carcinoma: Report of 2 cases. Virchows Arch. 2013;463:349. FI: 2,676(Q2). ( Meeting Abstract)

Larrinaga G, Sanz B, Blanco L, Perez I, Candenas ML, Pinto FM, et al. Cannabinoid CB1 receptor is expressed in chromophobe renal cell carcinoma and renal oncocytoma. Clin Biochem. 2013;46:638-41. FI: 2,076(Q2).

López JI. Renal tumors with clear cells.A review. Pathol Res Pract. 2013;209:137-46. FI: 1,213(Q4)

Nunes-Xavier CE, Martín-Pérez J, Elson A, Pulido R. Protein tyrosine phosphatases as novel targets in breast cancer therapy. Biochim Biophys Acta. 2013;1836:211-26. FI: 9,033(Q1)

Pulido R, Stoker AW, Hendriks WJ. PTPs emerge as PIPs: protein tyrosine phosphatases with lipid-phosphatase activities in human disease. Hum Mol Genet. 2013;22:R66-76 FI: 7,692(Q1)

Berthier A, Jiménez-Sáinz J, Pulido R. PINK1 regulates histone H3 trimethylation and gene expression by interaction with the polycomb protein EED/WAIT1. Proc Natl Acad Sci USA. 2013;110:14729-34. FI: 9,737(Q1)

Tesis

Autor/a: Laura Zaldumbide Dueñas. Título: La heterogeneidad intratumoral en el carcinoma renal de células claras. Director/a: Dr. Jose Ignacio López Fernández de Villaverde. UPV/EHU

Autor/a: Pedro Varela Gonzalez. Título: Actividad y expresión de enzimas convertidoras de angiotensina en neoplasias renales. Director/a: Dr. José Ignacio López Fernández de Villaverde, Dr. Gorka Larrinaga Embeitia. UPV/EHU